Resistin/uric acid index as a marker of metabolic syndrome in females with obesity
Main finding · Metabolic syndromeResult — go to the resultOdds ratio 1.71 95% CI 1.22–2.69Authors' conclusion
Resistin/uric acid index is related with Metabolic syndrome (MS) risk and criteria of it in a population of Caucasian females with obesity and this index is a correlated with glucose levels, insulin levels and insulin resistance (HOMA-IR).
Study context
- Population
- Caucasian females with obesity
- Participants
- 571 females
- Exposure
- High vs low resistin/uric acid index
- Outcome
- Relationship of resistin/uric acid index with metabolic syndrome
Main finding
Metabolic syndrome
Odds ratio
1.71
95% CI 1.22–2.69
P = 0.02
High resistin/uric acid indexvs Low index
OR 1.71 (95% CI 1.22–2.69); P = 0.02
As reported in the abstract
- Subjects with Metabolic Syndrome (MS)
- 249 (43.6%)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Hyperglycemia | 1.77 (1.10–2.92) | P = 0.02 | |
| Hypertension | 1.91 (1.36–3.01) | P = 0.01 | |
| Central obesity | 1.48 (1.15–1.84) | P = 0.03 | |
| 0.20.5125Odds ratio (log scale) |
Waist circumference, BP, glucose, insulin, HOMA-IR, uric acid, resistin (higher in high index)
- Waist circumference delta
- 3.1 ± 0.5 cm; p = 0.04
- Systolic BP delta
- 5.3 ± 3.6 mmHg; p = 0.01
- Diastolic BP delta
- 2.3 ± 0.4 mmHg; p = 0.02
- Glucose delta
- 7.5 ± 0.9 mg/dL; p = 0.01
- Insulin delta
- 2.5 ± 0.3 UI/L; p = 0.02
- HOMA-IR delta
- 0.7 ± 0.2 units; p = 0.03
- Uric acid delta
- 0.9 ± 0.2 mg/dl; p = 0.01
- Resistin delta
- 4.1 ± 0.4 ng/dl; p = 0.01
- Resistin/uric acid index delta
- 0.61 ± 0.01 mg/dl; p = 0.02
- Higher in high resistin/uric acid index group than low index group
Original publication
Resistin/uric acid index as a marker of metabolic syndrome in females with obesity. Int J Obes (Lond). Published 2 March 2023. doi:10.
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