Lipids & metabolic liver disease
Repeated detection of non‐alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults
Authors' conclusion
Repeated detection of NAFLD influenced the incidence risk of type 2 diabetes in young adults, and a higher degree of repeated detection of NAFLD was independently associated with the risk of type 2 diabetes in young adults.
Study context
- Population
- Young adults aged 20–39 years who underwent health screening four times between 2009 and 2013, Korea; Non-alcoholic fatty liver disease (NAFLD) defined as fatty liver index (FLI) ≥60approximately
- Participants
- 1,125,015 adults
- Exposure
- Repeated detection of NAFLD scores 1, 2, 3 and 4 vs 0
- Outcome
- Incident T2D
Methodological detailsKorean National Health Insurance Service data, multivariable-adjusted
- Korean National Health Insurance Service data
- Multivariable-adjusted
Main finding
As reported in the abstract
Incident T2D by repeated detection of NAFLD score
- T2D incidence risk increased significantly with repeated detection of the NAFLD score
- HRs for T2D showed a significant continuous positive linear association with increasing weighted repeated NAFLD score
Observational data: associations, not effects.
Further findings
Weighted repeated NAFLD score (0–8; 0 for FLI <30, 1 for 30 ≤ FLI < 60, 2 for FLI ≥60) and incident T2D
- HRs showed a significant continuous positive linear association with increasing scores
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Repeated detection of non‐alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults. Diabetes Obes Metab. Published 23 October 2023. doi:10.
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