Relationship between weight‐adjusted‐waist index and all‐cause and cardiovascular mortality in individuals with type 2 diabetes
Authors' conclusion
Our study indicates that WWI has a long-term synergistic negative impact on all-cause mortality and cardiovascular mortality in individuals with type 2 diabetes. The WWI is an independent predictor of mortality in individuals with type 2 diabetes.
Study context
- Population
- Individuals with T2D, National Health and Nutrition Examination Survey (NHANES) 1999–2018 and UK Biobank
- Exposure
- Highest vs lowest WWI quartile
- Outcome
- All-cause mortality
Methodological detailsNHANES 1999–2018 and UK Biobank, Cox proportional hazards models, restricted cubic spline curves
- NHANES 1999–2018 and UK Biobank
- Cox proportional hazards models
- Restricted cubic spline curves
Main finding
As reported in the abstract
All-cause death
Highest WWI quartile vs Lowest WWI quartileHazard ratio (95% CI)
UK Biobank; fully adjusted model
1.846(1.687–2.019)
NHANES; fully adjusted model
1.727(1.378–2.163)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Cardiovascular deathHighest WWI quartilevs Lowest WWI quartileUK Biobank; fully adjusted model | 2.118 (1.783–2.517) | |
| Cardiovascular deathHighest WWI quartilevs Lowest WWI quartileNHANES; fully adjusted model | 1.719 (1.139–2.595) | |
| 0.20.5125Hazard ratio (log scale) |
Original publication
Relationship between weight‐adjusted‐waist index and all‐cause and cardiovascular mortality in individuals with type 2 diabetes. Diabetes Obes Metab. Published 18 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →