Relationship Between Serum 25-Hydroxyvitamin D and Bone Mineral Density, Fracture Risk, and Bone Metabolism in Adults With Osteoporosis/Fractures
An erratum to this article was published (Endocr Pract, Sep 2024 ↗)
Authors' conclusion
Vitamin D deficiency is significantly associated with decreased total hip and femoral neck BMD and increased fracture risk as assessed by Fracture Risk Assessment Tool. In those with osteoporosis/fractures, vitamin D is implicated in the causal relationship between bone remodeling and BMD. Assessing vitamin D status is imperative for those at risk for osteoporosis/fractures.
Study context
- Population
- Menopausal females and males ≥50 years with osteoporosis/fractures, recruited September 2016 to September 2021
- Participants
- 3,003 females
- Exposure
- 25D categories: <20 vs 20 to 29 vs ≥30 ng/mL
- <20 ng/mLn = 720
- 20 to 29 ng/mLn = 1,338
- ≥30 ng/mLn = 945reference
- Outcome
- Association of 25(OH)D with BMD, fracture risk and bone metabolism
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Observational data: associations, not effects.
Original publication
Relationship Between Serum 25-Hydroxyvitamin D and Bone Mineral Density, Fracture Risk, and Bone Metabolism in Adults With Osteoporosis/Fractures. Endocr Pract. Published 30 April 2024. doi:10.
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