Relationship between life’s essential 8, vitamin D, and cardiometabolic outcomes
Authors' conclusion
These findings underscore that higher CVH scores, assessed by Life's Essential 8, are associated with lower risks of cardiometabolic outcomes. Improving CVH contributes to reducing the burden of disease and promoting human health.
Study context
- Population
- Adult participants of the National Health and Nutrition Examination Survey (2007–2018)
- Participants
- 21,913 participants
- Exposure
- Low vs moderate vs high cardiovascular health (CVH)
- Low CVHn = 6,193
- Moderate CVHn = 14,080
- High CVHn = 1,640
- Outcome
- Association between CVH and cardiometabolic outcomes
Main finding
As reported in the abstract
Cardiometabolic outcomes
Observational data: associations, not effects.
Further findings
Predictive ability of CVH metrics (ROC)
- Blood glucose and blood pressure had higher predictive values for CVD, CKD, hypertension and diabetes
Interaction with vitamin D
- Significant interaction between CVH and vitamin D
Original publication
Relationship between life’s essential 8, vitamin D, and cardiometabolic outcomes. Diabetes Res Clin Pract. Published 22 February 2025. doi:10. 1016/ j. diabres. 2025. 112057
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