Reduction of Postprandial Glucose Excursions in Adults, Adolescents, and Children with Type 1 Diabetes Using Ultra-Rapid Lispro Insulin and Control-IQ+ Technology
Main finding · Postprandial glucoseResult — go to the resultAdjusted mean difference −11 mg/dLAuthors' conclusion
In conclusion, compared with insulin lispro, the use of URLi with Control-IQ+ technology modestly improved postprandial glucose excursions with the greatest amount of improvement for breakfast and in those with insulin resistance.
Study context
- Population
- Adults, adolescents and children with T1D using Control-IQ+ technology
- Participants
- 176 adults
- Comparison
- Ultra-rapid lispro vs insulin lispro, with Control-IQ+ technology
- Outcome
- Postprandial glucose
- Follow-up
- 60 min
Main finding
As reported in the abstract
Adjusted mean difference
−11 mg/dL
P < 0.001
By group
Further findings
| Outcome | Adjusted mean difference (mg/dL) | P value |
|---|---|---|
| Mean glucose excursion | −4 | P = 0.001 |
mg/dL
- Mean glucose excursion — AMD after breakfast
- −9
- Mean glucose excursion — AMD after lunch
- −2
- Mean glucose excursion — AMD after dinner
- −2
Mean glucose excursion by insulin-to-carbohydrate ratio (ICR)
mg/dL
- AMD, ICR <5 g/U
- −11
- AMD, ICR 5-15 g/U
- −2
- AMD, ICR >15 g/U
- 1
Original publication
Reduction of Postprandial Glucose Excursions in Adults, Adolescents, and Children with Type 1 Diabetes Using Ultra-Rapid Lispro Insulin and Control-IQ+ Technology. Diabetes Technol Ther. Published 2 April 2025. doi:10. 1089/ dia. 2025. 0077
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