Reduced heart rate variability in people with type 1 diabetes and elevated diabetes distress: Results from the longitudinal observational DIA‐LINK1 study
Main finding · HRV across 26 days, by diabetes distressResult — go to the resultβ −0.28Authors' conclusion
Diabetes distress is a clinically meaningful psychosocial stressor that could play a role in the cardiovascular health of people with type 1 diabetes. These findings highlight the need for integrated psychosocial care in diabetes management.
Study context
- Population
- People with T1D; mean age 38.3 ± 13.1 years, HbA1c 8.6 ± 1.9%; Heart rate variability (HRV) by wrist-worn tracker and glucose by continuous glucose monitoring (CGM) daily for 26 daysanalysed
- Participants
- 149 people
- Exposure
- Elevated vs no elevated diabetes distress in relation to HRV
- Outcome
- Day-to-day HRV
- Follow-up
- 26 days
Methodological detailsnon-interventional, longitudinal, multilevel modelling
- Non-interventional
- Longitudinal
- Multilevel modelling
Main finding
HRV across 26 days, by diabetes distress
β
−0.28
P = 0.004
As reported in the abstract
Observational data: associations, not effects.
Further findings
Elevated depressive symptoms and HRV · 26 days
- Not significantly associated with HRV (β)
- −0.18; p = 0.074
Higher daily exposure to hyperglycaemia and HRV · 26 days
- Associated with reduced HRV (β)
- −0.44; p = 0.044
Higher average exposure to hypoglycaemia and HRV · 26 days
- Associated with reduced HRV (β)
- −0.18; p = 0.042
Higher HbA1c and HRV · 26 days
- Associated with reduced HRV (β)
- −0.20; p = 0.018
Sensitivity analysis: HRV averaged across all days
- Corroborated these results
Original publication
Reduced heart rate variability in people with type 1 diabetes and elevated diabetes distress: Results from the longitudinal observational DIA‐LINK1 study. Diabet Med. Published 26 January 2023. doi:10.
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