Fall in prevalence of impaired awareness of hypoglycaemia in individuals with type 1 diabetes
Authors' conclusion
Among individuals with type 1 diabetes and high use of sensor technology, the current prevalence of IAH was 16%, about 50% lower as compared to previous years.
Study context
- Population
- Adults with T1D from a diabetes outpatient clinic; 51.2% male, mean age 51.3 ± 15.9 years, median diabetes duration 30 [16–40] years, mean HbA1c 60 ± 12 mmol/mol (7.7 ± 1.1%); sensors used by 85%
- Participants
- 488 adults
- Exposure
- Current impaired awareness of hypoglycaemia (IAH) prevalence vs previous assessments in 2006, 2010 and 2016
- 2020n = 488
- Outcome
- Prevalence of IAH (modified Clarke questionnaire)
Methodological detailsrepeated assessments compared with 2006, 2010 and 2016
- Repeated assessments compared with 2006, 2010 and 2016
Main finding
As reported in the abstract
February 2020 through April 2021
IAH present in current cohort (2020–2021)
78
16.0%
Prevalence of IAH in 2006
32.5%
Prevalence of IAH in 2010
32.3%
Prevalence of IAH in 2016
30.1%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| History of severe hypoglycaemiaBetween 2006 and 2010 · trend across assessments | p for trend 0.010 |
- History of severe hypoglycaemia — History of severe hypoglycaemia in current cohort (2020–2021)
- 86 (17.6%)
- History of severe hypoglycaemia — Severe hypoglycaemia reported in 2006
- 21.2%
- History of severe hypoglycaemia — Severe hypoglycaemia reported in 2010
- 46.7%
- History of severe hypoglycaemia — Severe hypoglycaemia reported in 2016
- 49.8%
Persistent IAH across sequential assessments
- Persistent IAH between 2006 and 2016
- 74.0% and 63.6%
- Persistent IAH in 2020
- 32.5%
Original publication
Fall in prevalence of impaired awareness of hypoglycaemia in individuals with type 1 diabetes. Diabet Med. Published 21 January 2023. doi:10. 1111/ dme. 15042
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