Type 1 diabetes

Fall in prevalence of impaired awareness of hypoglycaemia in individuals with type 1 diabetes

Diabet MedPublished Cross-sectional study

Authors' conclusion

Among individuals with type 1 diabetes and high use of sensor technology, the current prevalence of IAH was 16%, about 50% lower as compared to previous years.

Study context

Population
Adults with T1D from a diabetes outpatient clinic; 51.2% male, mean age 51.3 ± 15.9 years, median diabetes duration 30 [16–40] years, mean HbA1c 60 ± 12 mmol/mol (7.7 ± 1.1%); sensors used by 85%
Participants
488 adults
Exposure
Current impaired awareness of hypoglycaemia (IAH) prevalence vs previous assessments in 2006, 2010 and 2016
  • 2020n = 488
Outcome
Prevalence of IAH (modified Clarke questionnaire)
Methodological detailsrepeated assessments compared with 2006, 2010 and 2016
  • Repeated assessments compared with 2006, 2010 and 2016

Main finding

As reported in the abstract

February 2020 through April 2021

IAH present in current cohort (2020–2021)

78

16.0%

Prevalence of IAH in 2006

32.5%

Prevalence of IAH in 2010

32.3%

Prevalence of IAH in 2016

30.1%

Observational data: associations, not effects.

Further findings

OutcomeP value
History of severe hypoglycaemiaBetween 2006 and 2010 · trend across assessmentsp for trend 0.010
History of severe hypoglycaemia — History of severe hypoglycaemia in current cohort (2020–2021)
86 (17.6%)
History of severe hypoglycaemia — Severe hypoglycaemia reported in 2006
21.2%
History of severe hypoglycaemia — Severe hypoglycaemia reported in 2010
46.7%
History of severe hypoglycaemia — Severe hypoglycaemia reported in 2016
49.8%

Persistent IAH across sequential assessments

Persistent IAH between 2006 and 2016
74.0% and 63.6%
Persistent IAH in 2020
32.5%

Original publication

Fall in prevalence of impaired awareness of hypoglycaemia in individuals with type 1 diabetes. Diabet Med. Published 21 January 2023. doi:10.1111/dme.15042

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