Endocrine oncology

Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement

Lancet Diabetes EndocrinolPublished Review and statement

Scope

As issued by the authors

Redifferentiation therapy (mitogen-activated protein kinase (MAPK) inhibitors before high activity 131I) in unresectable or metastatic radioactive iodine refractory follicular cell-derived thyroid cancer: prospective trial and case report results (iodine uptake restoration 33% to 95%; tumour response 11% to 80%), trial design differences, dosimetry, and key questions for future trials

Original publication

Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement. Lancet Diabetes Endocrinol. Published 30 April 2025. doi:10.1016/s2213-8587(25)00064-6

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