Endocrine oncology

Multicenter Study on the Clinical Characteristics, Diagnosis, and Treatment Outcomes of Insulinoma: Insights From 15 Medical Centres

Clin Endocrinol (Oxf)Published Retrospective multicentre cohort study

Authors' conclusion

This study emphasises that early diagnosis and intervention, particularly in patients with a history of neurological or psychiatric issues, postprandial symptoms, or rapid symptom improvement after treatment, can lead to significantly better outcomes.

Study context

Population
Adults diagnosed with insulinoma 2018–2023 at 15 medical centres
Participants
76 adults15 centres
Exposure
Men vs women
Outcome
Clinical characteristics, diagnosis and treatment outcomes

Main finding

As reported in the abstract

No significant gender differences in glucose and insulin during hypoglycaemia; men had higher C-peptide
p < 0.05

Observational data: associations, not effects.

Original publication

Multicenter Study on the Clinical Characteristics, Diagnosis, and Treatment Outcomes of Insulinoma: Insights From 15 Medical Centres. Clin Endocrinol (Oxf). Published 25 April 2025. doi:10.1111/cen.15255

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