Nomogram to predict the prognostic value of tumor deposits for patients with papillary thyroid carcinoma
Authors' conclusion
The presence of TD was significantly associated with poor prognosis in PTC patients. TD showed promising efficacy as a potential prognostic indicator for PTC patients.
Study context
- Population
- Patients with PTC undergoing surgery between 2015 and 2021
- Participants
- 541 patients
- Exposure
- TD vs non-TD
- Outcome
- DFS
Methodological detailsnomogram development
- Nomogram development
Main finding
As reported in the abstract
DFS (recurrence risk), multivariate Cox regression
TD an independent prognostic factor for disease-free survival (DFS); increased risk of recurrence
2.501-fold
P < 0.001
Observational data: associations, not effects.
Further findings
Prevalence of TD
- TD identified in patients
- 16.1%
Aggressive features with TD
- TD had higher rate of aggressive features (microscopic and gross extrathyroidal extension, recurrent laryngeal nerve and esophagus invasion, prevertebral fascia involvement or carotid artery/internal jugular vein encasement, extranodal extension, advanced clinical stage, tumor recurrence, distant metastasis)
- all P < 0.05
Nomogram performance for DFS
- Good discrimination and calibration, C-index
- 0.79
Original publication
Nomogram to predict the prognostic value of tumor deposits for patients with papillary thyroid carcinoma. Eur Thyroid J. Published 16 April 2025. doi:10.
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