Red blood cells in prediabetes: Early alterations, progressive trajectories, and clinical potential
Authors' conclusion
In conclusion, RBCs in prediabetes and diabetes are not merely mirrors of glycemia but appear to be hubs where altered oxidative stress, metabolism, and vascular biology converge.
Study context
- Population
- Prediabetes (and type 2 diabetes)
- Outcome
- RBC dysfunction in prediabetes
Main finding
As reported in the abstract
- Evidence synthesized on altered redox status, membrane composition, morphology, rheology, RBC indices and function in prediabetes
- Hypothesis-generating framework proposed of progressive, plateau, late and non-linear (peak, trough, biphasic) trajectories as glycemia worsens; warrants prospective validation
- Diagnostic, therapeutic and screening potential of RBC markers evaluated, with confounders that may limit clinical utility
Original publication
Red blood cells in prediabetes: Early alterations, progressive trajectories, and clinical potential. Diabetes Res Clin Pract. Published 22 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →