Recent Trends in Diabetic and Nondiabetic Neuropathies: A Retrospective Hospital-based Nationwide Cohort Study
Authors' conclusion
Using a nationally representative database of hospital-admitted cases, we found that the incidence rates of DN and non-DN increased from 2010 to 2019. The main contributors were type 2 diabetes, inflammatory polyneuropathy, and uremic neuropathy.
Study context
- Population
- Hospitalizations with a primary or secondary discharge ICD-10 diagnosis code of neuropathy, Romania, 2010–2019
- Participants
- 1,725,729 hospitalizations
- Exposure
- Diabetic neuropathy vs nondiabetic neuropathy
- DNn = 769,324
- non-DNn = 956,405
- Outcome
- Trends in the incidence of DN and non-DN
- Follow-up
- 2010–2019
Methodological detailshospital-based, nationwide
- Hospital-based
- Nationwide
Main finding
As reported in the abstract
Incidence rate trend
DN
1.4%/year
mean
non-DN
4.3%/year
mean
Observational data: associations, not effects.
Further findings
Sex distribution
- Women accounted for more DN cases
- 40 0 936- 52.1%
- Men accounted for more non-DN cases
- 63 7 968- 61.0%
DN by diabetes type and neuropathy type
- T2D responsible for overall increase in DN incidence; in T1D incidence decreased
- Diabetic polyneuropathy predominant in both types; autonomic neuropathy incidence 10 to 20 times lower than polyneuropathy
Non-DN incidence increase by cause
- Inflammatory polyneuropathies
- +3.8%
- Uremic neuropathy
- +10.3%
Original publication
Recent Trends in Diabetic and Nondiabetic Neuropathies: A Retrospective Hospital-based Nationwide Cohort Study. Endocr Pract. Published 25 July 2024. doi:10. 1016/ j. eprac. 2024. 07. 011
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