Type 2 & other diabetes

Reallocating morning physical activity to later‐day activity and its association with type 2 diabetes incidence: The Maastricht Study

Diabetes Obes MetabPublished Prospective cohort study

Authors' conclusion

Later-day physical activity, particularly in the afternoon, was associated with a lower incidence of T2DM, independent of intensity. This highlights the potential relevance of activity timing in relation to T2DM incidence.

Study context

Population
Adults without diabetes from The Maastricht Study cohort; age 59.2 ± 8.6 years; 56.3% women
Participants
4,615 adults
Exposure
Time-of-day-specific physical activity (morning, afternoon, evening, night) and reallocation of morning activity to later in the day
Outcome
Incident T2D
Follow-up
median 8.2-year follow-up
Methodological detailsdevice-based physical activity (activPAL, 7 days), Cox proportional hazard and isotemporal substitution models, adjusted for sociodemographic and lifestyle factors
  • Device-based physical activity (activPAL, 7 days)
  • Cox proportional hazard and isotemporal substitution models
  • Adjusted for sociodemographic and lifestyle factors

Main finding

As reported in the abstract

Incident T2D per additional 10 min/day of activity by time of day

Afternoon LPA, HR per 10 min/day

0.82

95% CI 0.70–0.97

Afternoon MVPA, HR per 10 min/day

0.85

95% CI 0.72–1.00

Evening MVPA, HR (0.45-0.93)

0.65

Night-time MVPA, HR, increased risk (1.30-10.17)

3.64

Observational data: associations, not effects.

Further findings

Incident T2D · median 8.2-year follow-up

Developed T2D during follow-up
168 participants (3.6%)

Isotemporal substitution: reallocating 10 min of morning activity

Morning LPA to afternoon LPA, HR (0.54-0.95)
0.71
Morning MVPA to evening MVPA, HR (0.43-0.96)
0.64
No other significant associations

Original publication

Reallocating morning physical activity to later‐day activity and its association with type 2 diabetes incidence: The Maastricht Study. Diabetes Obes Metab. Published 13 January 2026. doi:10.1111/dom.70438

Composed by AI from the published abstract and checked against it. How Briefs are made →

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