Real-World Clinical Impact of Using Personal Glucose Targets in a Hybrid Closed-Loop System Differs According to Age
Authors' conclusion
Personal glucose targets are frequently used, with clinical impact differing depending on user-age. Adjusting glucose targets may help to achieve recommended glycemic targets and individual glycemic goals.
Study context
- Population
- Real-world CamAPS FX users aged 1 to 90 years from 11 countries, with ≥8 weeks of closed-loop use between December 1, 2022 and November 30, 2023
- Participants
- 8,604 users
- Exposure
- Personal glucose targets vs default target in CamAPS FX HCL
- Outcome
- Use of personal glucose targets and glycemic control by target and age-group
Methodological detailsreal-world data, 11 countries, Every sensor glucose reading matched to the user-specified glucose target
- Real-world data
- 11 countries
- Every sensor glucose reading matched to the user-specified glucose target
Main finding
As reported in the abstract
- Personal glucose targets used by very young children
- >50%
- Personal glucose targets used by school-aged children
- >40%
- Default target use in all other age-groups (of the time)
- 65%-68%
- Personal targets >120 mg/dL associated with TIR
- <70%
- Time <70 mg/dL across targets, apart from lowest (80-89 mg/dL)
- <4%
- Older adults achieved TIR across all targets
- ≥70%
- Very young children and young adults achieved TIR >70% only with targets below default; in very young children associated with time <70 mg/dL of
- >4%
Observational data: associations, not effects.
Original publication
Real-World Clinical Impact of Using Personal Glucose Targets in a Hybrid Closed-Loop System Differs According to Age. Diabetes Technol Ther. Published 5 September 2025. doi:10.
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