Evaluating the Impact of Applying Personal Glucose Targets in a Closed-Loop System for People With Type 1 Diabetes
Authors' conclusion
Discrete study populations showed differences in glucose control when applying similar personal targets.
Study context
- Population
- Participants with T1D using the CamAPS FX hybrid closed-loop app in five RCTs5 RCTs
- Comparison
- Personal glucose targets vs default target bin (5.5-6.0 mmol/L) in CamAPS FX hybrid closed-loop
Primary result
As reported in the abstract
TIR (3.9-10.0 mmol/L [70-180 mg/dL])
Each group vs default target binMean difference, percentage points (95% CI)P value
6.5-7.0 mmol/L
−3.2(−5.3 to −1.2)
P < 0.0017.0-7.5 mmol/L
−10.8(−14.1 to −7.6)
P < 0.001- Days with a target outside the default target bin
- 20.3%
Further findings
| Outcome | Estimate | P value |
|---|---|---|
| Time <3.9 mmol/L [<70 mg/dL]6.5-7.0 mmol/L vs Default target bin | −1.85 percentage points (95% CI −2.37 to −1.34) | P < 0.001 |
| Time <3.9 mmol/L [<70 mg/dL]7.0-7.5 mmol/L vs Default target bin | −2.68 percentage points (95% CI −3.49 to −1.86) | P < 0.001 |
Original publication
Evaluating the Impact of Applying Personal Glucose Targets in a Closed-Loop System for People With Type 1 Diabetes. J Diabetes Sci Technol. Published 20 December 2022. doi:10.
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