Real-Life Use of Automated Insulin Delivery in Individuals With Type 2 Diabetes
Authors' conclusion
Real-life use of AID led to a rapid and sustained improvement of glycemic control in individuals with T2D.
Study context
- Population
- Individuals with T2D transitioning from predictive low-glucose suspend (PLGS) to automated insulin delivery (AID) in real-life settingssame individuals, PLGS then AID
- Participants
- 796 individuals
- Exposure
- AID vs prior PLGS
- Outcome
- Change of TIR (70-180 mg/dL) from PLGS to AID
Methodological detailsreal-life settings, before-after (PLGS to AID)
- Real-life settings
- Before-after (PLGS to AID)
Main finding
As reported in the abstract
TIR (70-180 mg/dL)
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
TAR · TAR decreased with AID
P < 0.001
TDI · TDI increased with AID
P < 0.001
Glycemic improvement by PLGS-period glycemic control
- Glycemic improvements more pronounced in those with worse glycemic control during PLGS use
- P < 0.001
Safety
- No significant change to TBR with AID vs PLGS
Original publication
Real-Life Use of Automated Insulin Delivery in Individuals With Type 2 Diabetes. J Diabetes Sci Technol. Published 24 August 2024. doi:10. 1177/ 19322968241274786
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