Diabetes technology

Real-Life Use of Automated Insulin Delivery in Individuals With Type 2 Diabetes

J Diabetes Sci TechnolPublished Retrospective cohort study

Authors' conclusion

Real-life use of AID led to a rapid and sustained improvement of glycemic control in individuals with T2D.

Study context

Population
Individuals with T2D transitioning from predictive low-glucose suspend (PLGS) to automated insulin delivery (AID) in real-life settingssame individuals, PLGS then AID
Participants
796 individuals
Exposure
AID vs prior PLGS
Outcome
Change of TIR (70-180 mg/dL) from PLGS to AID
Methodological detailsreal-life settings, before-after (PLGS to AID)
  • Real-life settings
  • Before-after (PLGS to AID)

Main finding

As reported in the abstract

TIR (70-180 mg/dL)

P < 0.001

Observational data: associations, not effects.

Secondary outcomes

TAR · TAR decreased with AID

P < 0.001

TDI · TDI increased with AID

P < 0.001

Glycemic improvement by PLGS-period glycemic control

Glycemic improvements more pronounced in those with worse glycemic control during PLGS use
P < 0.001

Safety

No significant change to TBR with AID vs PLGS

Original publication

Real-Life Use of Automated Insulin Delivery in Individuals With Type 2 Diabetes. J Diabetes Sci Technol. Published 24 August 2024. doi:10.1177/19322968241274786

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