Radiofrequency Ablation of Toxic Thyroid Nodules: An Early Experience of a Single Institution in the United States
Authors' conclusion
In our early experience, RFA is a safe and effective method for treating hyperfunctioning thyroid nodules of benign etiologies. To further validate and support these findings, expansion of this cohort and more extensive follow-up will allow us to better characterize the outcomes of RFA and compare this approach to both surgical and other minimally invasive thermal ablative approaches.
Study context
- Population
- Patients with symptomatic hyperthyroidism from toxic nodules (toxic adenomas and multinodular goiters), single US institution
- Participants
- 41 patients
- Outcome
- Nodule volume reduction (US)
- Follow-up
- 12 months
Methodological detailssingle-institution, office-based, Nodule volume recorded by US at ≈1, 3, 6 and 12 months after radiofrequency ablation (RFA)
- Single-institution
- Office-based
- Nodule volume recorded by US at ≈1, 3, 6 and 12 months after RFA
Main finding
As reported in the abstract
RFA
80.57%
mean
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Sustained remission from hyperthyroid state | RFA 35 of 41 |
Sustained remission from hyperthyroid state
- Significant improvement in cosmetic and clinical symptoms
Safety
- Pain was the most frequent complication; it did not cause early termination of the procedure or affect outcomes
Original publication
Radiofrequency Ablation of Toxic Thyroid Nodules: An Early Experience of a Single Institution in the United States. Endocr Pract. Published 11 December 2024. doi:10.
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