Effects of Ultrasound-Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules, Using EchoLaser – Results of a Pilot Study in the United States
Authors' conclusion
This study demonstrated the feasibility of performing laser ablation in a clinical setting in the United States. Reduction in nodule volume and symptoms were observed, and the procedure was tolerated well by the subjects.
Study context
- Population
- Adults with normal thyroid function and symptomatic benign thyroid nodules >29 mm and ≤60 mm with <20% cystic area by US; outpatient setting, United States9 completed 12-month follow-up
- Participants
- 10 adults
- Outcome
- Efficacy of single US-guided laser ablation on symptomatic benign thyroid nodules (nodule volume reduction)
- Follow-up
- 12 months
Methodological detailssingle-center, nonrandomized, open label, Baseline nodule volumes 5.51 to 28.22 mL; total energy delivered 1477.00 to 7206.50 J
- Single-center
- Nonrandomized
- Open label
- Baseline nodule volumes 5.51 to 28.22 mL; total energy delivered 1477.00 to 7206.50 J
Main finding
As reported in the abstract
Average nodule volume reduction
Average nodule volume reduction at 12 months (9 patients)
71.087%
Observational data: associations, not effects.
Further findings
Nodule visibility from >1 m away
- Visible at baseline
- all 10 subjects
- Not visible at 3 months
- 8 of 10
- Not visible at 12 months
- 6 of 9
Willingness to undergo procedure again
- Most subjects reported they would likely undergo the procedure again
Safety
- No significant adverse events were reported
Original publication
Effects of Ultrasound-Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules, Using EchoLaser – Results of a Pilot Study in the United States. Endocr Pract. Published 11 September 2023. doi:10.
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