Lipids & metabolic liver disease
Racial Discrimination and Metabolic Syndrome in Young Black Adults
Main finding · MetS diagnosisResult — go to the resultOdds ratio 1.10 95% CI 1.01–1.20Authors' conclusion
This study suggests that racial discrimination in late adolescence is associated with MetS among Black young adults through biobehavioral pathways. Thus, health interventions for MetS in Black adults will need to contend with sleep behaviors and inflammatory intermediaries as well as address and reduce exposure to racial discrimination to narrow disparities and promote health equity.
Study context
- Population
- Rural Black adolescents transitioning into early adulthood, SHAPE Project, rural counties of Georgia, 2009–2021of 500 enrolled
- Participants
- 322 adolescents
- Exposure
- More frequent vs less frequent exposure to racial discrimination
- Outcome
- MetS per IDF guidelines
- Follow-up
- Ages 25 and 31 years
Main finding
MetS diagnosis · age 31 years
Odds ratio
1.10
95% CI 1.01–1.20
P = 0.03
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | B (95% CI) | P value |
|---|---|---|
| suPAR levels · age 25 yearsHigher suPAR | 0.006 (0.001–0.011) | P = 0.01 |
| Sleep problems · age 25 yearsMore sleep problems | 0.062 (0.028–0.097) | P < 0.001 |
Indirect pathways to metabolic syndrome (MetS) · age 25 years
- Indirect pathway via suPAR (b)
- 0.015; 95% CI, 0.002-0.037
- Indirect pathway via sleep problems (b)
- 0.020; 95% CI, 0.002-0.047
Sex × discrimination interaction
- No significant interactions between sex and discrimination
Original publication
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