Reproductive endocrinology

Quantitative effects of sex hormones on hair growth and patient satisfaction

J Clin Endocrinol MetabPublished Prospective longitudinal cohort study

Authors' conclusion

GAHT induces measurable, location-specific changes in terminal hair growth in transgender women and men, accompanied by improvements in body image and satisfaction.

Study context

Population
Transgender men and women initiating gender-affirming hormone therapy (GAHT), assessed at baseline, 3 and 12 months
Participants
36 men
Exposure
Transgender women vs Transgender men
  • Transgender womenn = 16
  • Transgender menn = 20
Outcome
Change in terminal hair density measured by digital microscopy
Follow-up
12 months

Main finding

As reported in the abstract

Change in terminal hair density (digital microscopy)
Transgender women: upper lip
−17 hairs/cm², CI −32, −2
Transgender women: chin
−28 hairs/cm², CI −47, −8
Transgender men: upper lip
+21 hairs/cm², CI 11-30
Transgender men: chin
+13 hairs/cm², CI 3-24
Transgender men: upper abdomen
+17 hairs/cm², CI 8-23
Transgender men: lower abdomen
+20 hairs/cm², CI 11-28
Transgender men: thighs
+14 hairs/cm², CI 7-21

Observational data: associations, not effects.

Further findings

Psychosocial outcomes (Body Appreciation Scale-2, satisfaction questionnaires)

Both groups reported improved body appreciation, satisfaction with hair growth and gender congruence

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Quantitative effects of sex hormones on hair growth and patient satisfaction. J Clin Endocrinol Metab. Published 8 April 2026. doi:10.1210/clinem/dgag139

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