Quantitative computed tomography provides improved accuracy for diagnosis of lumbar osteoporosis in patients with facet joint osteoarthritis: a cross-sectional study
Authors' conclusion
More severe FJOA was associated with higher aBMD on DXA and a lower vBMD on QCT. Additionally, the rate of lumbar osteoporosis detection was significantly higher with QCT than with DXA.
Study context
- Population
- Patients with facet joint osteoarthritis without spinal instrumentation surgery, spinal fractures of > 2 levels, spinal tumours or infections, or sacralization of lumbar spine (mean age 65.0 ± 10.7 years)155 (70.8%) women
- Participants
- 219 patients
- Exposure
- QCT vs DXA for detection of lumbar osteoporosis in patients with facet joint osteoarthritis
- Outcome
- Detection rate of lumbar osteoporosis, QCT vs DXA
Methodological detailssingle-centre, retrospective
- Single-centre
- Retrospective
Main finding
As reported in the abstract
Lumbar osteoporosis detection rate
P < 0.0001
Observational data: associations, not effects.
Further findings
Association of FJOA severity with areal BMD (aBMD) on DXA
| β (95% CI) | P value | |
|---|---|---|
| Slight-to-moderate FJOA | 0.31 (0.16–0.46) | P < 0.001 |
| Severe FJOA | 1.03 (0.79–1.27) | P < 0.001 |
| Outcome | Multivariable β (95% CI) | P value |
|---|---|---|
| Association of FJOA severity with vBMD on QCT | - 4.23 (- 7.68 to - 0.77) | P = 0.17 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Quantitative computed tomography provides improved accuracy for diagnosis of lumbar osteoporosis in patients with facet joint osteoarthritis: a cross-sectional study. Osteoporos Int. Published 27 July 2025. doi:10. 1007/ s00198-025-07600-3
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