Osteoporosis, bone & mineral

Quantitative computed tomography provides improved accuracy for diagnosis of lumbar osteoporosis in patients with facet joint osteoarthritis: a cross-sectional study

Osteoporos IntPublished Cross-sectional study

Authors' conclusion

More severe FJOA was associated with higher aBMD on DXA and a lower vBMD on QCT. Additionally, the rate of lumbar osteoporosis detection was significantly higher with QCT than with DXA.

Study context

Population
Patients with facet joint osteoarthritis without spinal instrumentation surgery, spinal fractures of > 2 levels, spinal tumours or infections, or sacralization of lumbar spine (mean age 65.0 ± 10.7 years)155 (70.8%) women
Participants
219 patients
Exposure
QCT vs DXA for detection of lumbar osteoporosis in patients with facet joint osteoarthritis
Outcome
Detection rate of lumbar osteoporosis, QCT vs DXA
Methodological detailssingle-centre, retrospective
  • Single-centre
  • Retrospective

Main finding

As reported in the abstract

Lumbar osteoporosis detection rate

P < 0.0001

Observational data: associations, not effects.

Further findings

Association of FJOA severity with areal BMD (aBMD) on DXA

β (95% CI)P value
Slight-to-moderate FJOA0.31 (0.16–0.46)P < 0.001
Severe FJOA1.03 (0.79–1.27)P < 0.001
OutcomeMultivariable β (95% CI)P value
Association of FJOA severity with vBMD on QCT- 4.23 (- 7.68 to - 0.77)P = 0.17

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Quantitative computed tomography provides improved accuracy for diagnosis of lumbar osteoporosis in patients with facet joint osteoarthritis: a cross-sectional study. Osteoporos Int. Published 27 July 2025. doi:10.1007/s00198-025-07600-3

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