Prunes preserve cortical density and estimated strength of the tibia in a 12-month randomized controlled trial in postmenopausal women: The Prune Study
Authors' conclusion
Prune consumption for 12 months preserved cortical bone structure and estimated bone strength at the weight-bearing tibia in postmenopausal women.
Study context
- Population
- Postmenopausal women (age 62.1 ± 5.0 yrs)
- Participants
- 78 / 79 / 78
- Comparison
- 50 g and 100 g prunes daily vs control
- Controln = 78reference
- 50 g Prunen = 79
- 100 g Prunen = 78
- Primary endpoint
- vBMD, bone geometry and estimated strength of the radius and tibia by peripheral quantitative computed tomography (pQCT)
- Follow-up
- 12 months
Methodological detailssingle-centre, parallel arm
- Single-centre
- Parallel arm
Primary result
As reported in the abstract
baseline to 12 months/post
- Decreased in Control vs no change in Pooled Prune
- Pooled Prune vs Control: P = 0.012 (group × time interaction, cortical volumetric BMD (vBMD))
- Pooled Prune vs Control: P = 0.024 (group × time interaction, SSI)
Original publication
Prunes preserve cortical density and estimated strength of the tibia in a 12-month randomized controlled trial in postmenopausal women: The Prune Study. Osteoporos Int. Published 13 February 2024. doi:10.
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