Prolactin measurements in a real-life setting: a population-based cohort study
Authors' conclusion
We found a substantial number of repeated prolactin measurements, many of which did not seem to lead to clinical action.
Study context
- Population
- Individuals with ≥1 serum prolactin measurement, Central Denmark Region (1.32 mill inhabitants), 2011–2022
- Participants
- 84,145 individuals
- Outcome
- Frequency and pattern of serum prolactin measurements
Methodological detailspopulation-wide, data warehouse
- Population-wide
- Data warehouse
Main finding
As reported in the abstract
- ≥1 elevated prolactin measurement
- 17,008 (20.3%)
- Incidence of ≥1 elevated prolactin
- 107 per 100.000 person-years
- Hyperprolactinemia (≥2 elevated prolactin concentrations)
- 5,810 individuals (73.9% female)
- Incidence of hyperprolactinemia
- 36.7 per 100.000 person-years
- Hyperprolactinemia treated with dopamine agonists
- 12.7%
Observational data: associations, not effects.
Original publication
Prolactin measurements in a real-life setting: a population-based cohort study. Pituitary. Published 25 March 2026. doi:10.
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