Prognostic value of the stress‐hyperglycaemia ratio in patients with moderate‐to‐severe coronary artery calcification: Insights from a large cohort study
Main finding · MACCEsResult — go to the resultAdjusted hazard ratio 1.50 95% CI 1.10–2.03Authors' conclusion
Patients with MSCAC showed a positive correlation between the SHR and MACCE rate over a 3-year follow-up period. The study showed that an SHR value of 0.83 is the key threshold, indicating a poor prognosis. Future large-scale multicentre investigations should be conducted to determine the predictive value of the SHR in patients with MSCAC.
Study context
- Population
- Patients with angiography-detected moderate-to-severe coronary artery calcification (MSCAC)
- Participants
- 3,841 patients
- Exposure
- Stress-hyperglycaemia ratio (SHR) tertiles: T3 vs T1
- Outcome
- MACCEs: all-cause death, non-fatal MI and non-fatal stroke
- Follow-up
- Median 3.11 years
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
MACCEs
Adjusted hazard ratio
1.50
95% CI 1.10–2.03
T3vs T1
aHR 1.50 (95% CI 1.10–2.03)
As reported in the abstract
- Major adverse cardiovascular and cerebrovascular events (MACCEs) recorded
- 241
- Highest incidence of MACCEs in SHR T3 (Kaplan-Meier)
- P < 0.001
- Significant positive association between SHR and MACCEs (restricted cubic spline), consistent after adjustment
- Pnon-linear = .794
Observational data: associations, not effects.
Original publication
Prognostic value of the stress‐hyperglycaemia ratio in patients with moderate‐to‐severe coronary artery calcification: Insights from a large cohort study. Diabetes Obes Metab. Published 27 August 2024. doi:10.
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