Primary Hyperparathyroidism due to Parathyroid Adenoma in Children and Adolescents
Authors' conclusion
PHPT in children and adolescents is often symptomatic and more severe than adults. The main cause is single parathyroid adenoma. Associated hypercalcemic syndromes were not found. Patients were cured after surgical removal of the adenoma without significant postoperative complications and no recurrence during 10.4 ± 5.9 years follow-up.
Study context
- Population
- Children and adolescents with primary hyperparathyroidism (PHPT), 2005–2022, single tertiary university medical center
- Participants
- 10 children
- Outcome
- Clinical and laboratory features of paediatric PHPT
- Follow-up
- At diagnosis
Methodological detailssingle-centre, tertiary university medical center
- Single-centre
- Tertiary university medical center
Main finding
As reported in the abstract
Mean age at diagnosis (years)
16.3 ± 1.3
Symptomatic patients
8
Mean calcium (mg/dL)
13.6 ± 2.5
Mean PTH (pg/mL)
204.8 ± 163.1
Observational data: associations, not effects.
Original publication
Primary Hyperparathyroidism due to Parathyroid Adenoma in Children and Adolescents. Endocr Pract. Published 29 March 2024. doi:10.
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