Type 2 & other diabetes

“Preventing the Progression: The Power of Lifestyle Interventions in Prediabetic Individuals—A Systematic Review”

Clin Endocrinol (Oxf)Published Systematic review of randomised controlled trials

Authors' conclusion

Culturally adapted lifestyle interventions show strong efficacy and scalability in reversing prediabetes and reducing progression to T2DM. Integration of such strategies into national diabetes prevention programs may enhance sustainable metabolic health and address the unique needs of high-risk populations.

Study context

Population
Adults (≥18 years) with prediabetes; RCTs from 2020 to 20256 RCTs
Comparison
Culturally tailored lifestyle interventions in prediabetes
Methodological detailsPRISMA-compliant, Quality assessed with Jadad scale and Downs & Black checklist
  • PRISMA-compliant
  • Quality assessed with Jadad scale and Downs & Black checklist

Pooled result

As reported in the abstract

  • Significant improvements in glycemic parameters, cardiometabolic profiles, and reductions in diabetes incidence
  • Yoga-based protocols: notable declines in HbA1c and stress biomarkers
  • Dietary counseling and formula diets achieved normoglycemia and metabolic benefits independent of weight loss
  • Long-duration interventions reduced frailty and disability risks

Original publication

“Preventing the Progression: The Power of Lifestyle Interventions in Prediabetic Individuals—A Systematic Review”. Clin Endocrinol (Oxf). Published 12 December 2025. doi:10.1111/cen.70077

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