Diabetes complications

Prevalence and risk factors for diabetic retinopathy at diagnosis of type 2 diabetes: an observational study of 77 681 patients from the Swedish National Diabetes Registry

BMJ Open Diabetes Res CarePublished Cross-sectional study

Authors' conclusion

Intensified focus on screening of T2D may be needed in Sweden in clinical practice since nearly one-fifth of persons have retinopathy at diagnosis of T2D. The prevalence of DR was higher in men, birthplace outside of Sweden, and those with a history of stroke, kidney disease, and hypertension.

Study context

Population
Individuals with newly diagnosed T2D in the Swedish National Diabetes Registry with a retinal photo <2 years after diagnosis; mean age 62.6 years, 41.1% females
Participants
77,681 individuals
Outcome
Proportion of patients with retinopathy (simplex or worse)
Follow-up
<2 years after diagnosis of T2D
Methodological detailsregistry-based, observational
  • Registry-based
  • Observational

Main finding

As reported in the abstract

Prevalence of DR at diagnosis of T2D

Had diabetic retinopathy (DR)

13 329

17.2%

Observational data: associations, not effects.

Further findings

Factors associated with DR (logistic regression)

Older age, aOR per 10-year increase
1.03 (1.01 to 1.05) (95% CI)
Men vs women, OR
1.10 (1.05 to 1.14)
Lower education, OR
1.08 (1.02 to 1.14) (95% CI)
Previous stroke, OR
1.18 (1.07 to 1.30) (95% CI)
CKD, OR
1.29 (1.07 to 1.56) (95% CI)
Acetylsalicylic acid treatment, OR
1.14 (1.07 to 1.21) (95% CI)
ACE inhibitors, OR
1.12 (1.05 to 1.19) (95% CI)
Alpha blockers, OR
1.41 (1.15 to 1.73) (95% CI)
Born in Asia vs Sweden, OR
1.16 (1.08 to 1.25) (95% CI)
Born in other European countries vs Sweden, OR
1.11 (1.05 to 1.18) (95% CI)

Original publication

Prevalence and risk factors for diabetic retinopathy at diagnosis of type 2 diabetes: an observational study of 77 681 patients from the Swedish National Diabetes Registry. BMJ Open Diabetes Res Care. Published 4 June 2024. doi:10.1136/bmjdrc-2023-003976

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