Diabetes complications

Temporal and regional trends in adults with diabetics kidney disease in the US from 1999 to 2020

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

This study reveals notable disparities in DKD mortality rates across demographic groups and geographic regions. NH American Indians or Alaska Natives, males, elderly individuals, rural residents, and those in the West region were disproportionately affected. Understanding these trends is crucial for developing targeted interventions to reduce DKD-related mortality and address healthcare disparities.

Study context

Population
Adults aged ≥25 years with diabetic kidney disease (DKD)-associated deaths, US, 1999–2020
Participants
528,430 deaths
Outcome
Trends in age-adjusted mortality rates (AAMRs) associated with DKD
Follow-up
1999 to 2020
Methodological detailsCDC WONDER mortality database, Joinpoint regression
  • CDC WONDER mortality database
  • Joinpoint regression

Main finding

As reported in the abstract

DKD mortality trends
  • Mortality rates increased over time
  • Males consistently had higher AAMR than females
  • Highest AAMR in NH American Indian or Alaska Native, followed by NH Blacks, Hispanics, NH Whites and NH Asians
  • Highest AAMR in the West, followed by Midwest, South and Northeast
  • Rural regions had higher AAMR than urban areas
  • Mortality rates increased with age

Observational data: associations, not effects.

Original publication

Temporal and regional trends in adults with diabetics kidney disease in the US from 1999 to 2020. Diabetes Res Clin Pract. Published 4 June 2024. doi:10.1016/j.diabres.2024.111729

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