Differential associations of risk factors with severe and non‐severe hypoglycaemia: the Hypoglycaemia Assessment Tool prospective observational study in people with insulin‐treated type 1 diabetes and type 2 diabetes
Authors' conclusion
The risk of severe versus non-severe hypoglycaemia differs in patients with T1D and T2D; sex, the use of a CGM and insulin pump, and geographical areas were differently associated with one type of hypoglycaemia than the other.
Study context
- Population
- Patients with insulin-treated T1D and T2D in 24 countries
- Participants
- 5,949 vs 12,914
- Exposure
- Risk factors for severe vs non-severe hypoglycaemia
- T1Dn = 5,949
- T2Dn = 12,914
- Outcome
- Differential association of risk factors with severe and non-severe hypoglycaemia
- Follow-up
- 4 weeks
Methodological details24 countries, 4-week period
- 24 countries
- 4-week period
Main finding
As reported in the abstract
Excess risk higher for severe than non-severe hypoglycaemia in females vs males with T2D
42%
Excess risk higher for severe than non-severe hypoglycaemia in T2D with vs without continuous glucose monitoring (CGM)
27%
Excess risk lower for severe than non-severe hypoglycaemia in T1D with vs without insulin pump
47%
Observational data: associations, not effects.
Further findings
4-week rate of non-severe hypoglycaemia (episodes per person)
Median age
| Outcome | T1D | T2D |
|---|---|---|
| 4-week rate of severe hypoglycaemia | 0.94 | 0.30 |
Original publication
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