Osteoporosis, bone & mineral

Prevalence of low vitamin D levels among older US Asian and Pacific Islander adults

Osteoporos IntPublished Cross-sectional study

Authors' conclusion

In a large US healthcare population of older Asian/PI adults, low 25(OH)D prevalence was 1.5- to 2.7-fold higher for Asian/PI compared to NHW adults, with substantial variation by sex and ethnicity.

Study context

Population
Asian/Pacific Islander (PI) and non-Hispanic White (NHW) adults aged 50–89 years with measured 25(OH)D in 2012–2019 and body mass index (BMI) (within ± 1 year), California healthcare system102,556 Asian/PI, 381,724 NHW
Participants
31,287 / 71,269 / 122,162 / 259,562
Exposure
Asian/PI vs NHW adults, by sex and ethnic subgroup
  • Asian/PI menn = 31,287
  • Asian/PI womenn = 71,269
  • NHW menn = 122,162reference
  • NHW womenn = 259,562reference
Outcome
Prevalence of low 25(OH)D < 20 ng/mL (50 nmol/L)
Methodological detailshealthcare-system population, modified Poisson regression, adjusted prevalence ratios
  • Healthcare-system population
  • Modified Poisson regression, adjusted prevalence ratios

Main finding

As reported in the abstract

Low 25(OH)D < 20 ng/mL

Observational data: associations, not effects.

Further findings

OutcomeaPRP value
aPR of low 25(OH)D vs NHW, menNative Hawaiian/PI men vs NHW men · adjusted for age, smoking, BMI, season of measurement2.70P < 0.001
aPR of low 25(OH)D vs NHW, menSouth Asian men vs NHW men · adjusted for age, smoking, BMI, season of measurement2.56P < 0.001
aPR of low 25(OH)D vs NHW, menVietnamese men vs NHW men · adjusted for age, smoking, BMI, season of measurement2.17P < 0.001
aPR of low 25(OH)D vs NHW, menChinese men vs NHW men · adjusted for age, smoking, BMI, season of measurement2.04P < 0.001
aPR of low 25(OH)D vs NHW, menKorean men vs NHW men · adjusted for age, smoking, BMI, season of measurement1.60P < 0.001
aPR of low 25(OH)D vs NHW, menFilipino men vs NHW men · adjusted for age, smoking, BMI, season of measurement1.58P < 0.001
aPR of low 25(OH)D vs NHW, menJapanese men vs NHW men · adjusted for age, smoking, BMI, season of measurement1.58P < 0.001
aPR of low 25(OH)D vs NHW, womenNative Hawaiian/PI women vs NHW women · adjusted for age, smoking, BMI, season of measurement2.34P < 0.001
aPR of low 25(OH)D vs NHW, womenSouth Asian women vs NHW women · adjusted for age, smoking, BMI, season of measurement2.07P < 0.001
aPR of low 25(OH)D vs NHW, womenVietnamese women vs NHW women · adjusted for age, smoking, BMI, season of measurement2.31P < 0.001
aPR of low 25(OH)D vs NHW, womenChinese women vs NHW women · adjusted for age, smoking, BMI, season of measurement1.89P < 0.001
aPR of low 25(OH)D vs NHW, womenKorean women vs NHW women · adjusted for age, smoking, BMI, season of measurement1.85P < 0.001
aPR of low 25(OH)D vs NHW, womenFilipino women vs NHW women · adjusted for age, smoking, BMI, season of measurement1.52P < 0.001
aPR of low 25(OH)D vs NHW, womenJapanese women vs NHW women · adjusted for age, smoking, BMI, season of measurement1.49P < 0.001

Low 25(OH)D prevalence by Asian/PI subgroup, men

Korean, Japanese, Filipino
17 to 18%
Chinese, Vietnamese
22 to 24%
South Asian
28%
Native Hawaiian/PI
35%

Low 25(OH)D prevalence by Asian/PI subgroup, women

Japanese, Filipina, Chinese, Korean
11 to 14%
South Asian, Vietnamese
17 to 18%
Native Hawaiian/PI
26%

Original publication

Prevalence of low vitamin D levels among older US Asian and Pacific Islander adults. Osteoporos Int. Published 29 August 2024. doi:10.1007/s00198-024-07197-z

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