Prevalence and outcome of metastases to the thyroid gland: a nationwide database study
Authors' conclusion
Clinically relevant metastases to the thyroid are relatively rare and occur in a large variety of tumor types.
Study context
- Population
- Patients with pathologically proven thyroid metastases in the Netherlands, 1989–2014 (PALGA database)463 with complete survival data
- Participants
- 575 patients
- Outcome
- Origin, timing and survival of patients diagnosed with thyroid metastases
Methodological detailsPALGA linked with Netherlands Cancer Registry
- PALGA linked with Netherlands Cancer Registry
Main finding
As reported in the abstract
Origin, timing and survival of thyroid metastases
- Primary tumour: lung
- 29.4%
- Primary tumour: kidney
- 16.5%
- Primary tumour: breast carcinoma
- 10.1%
- Median time from primary diagnosis to thyroid metastasis diagnosis
- 17.2 months
- Latency period over 10 years
- 36 patients
- Thyroid metastasis part of pathologically proven widespread disease
- 77%
- Median survival after diagnosis of thyroid metastasis
- 12.3 months
Observational data: associations, not effects.
Original publication
Prevalence and outcome of metastases to the thyroid gland: a nationwide database study. Eur Thyroid J. Published 10 August 2026. doi:10.
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