Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies
Authors' conclusion
Six integrated trajectory patterns of prenatal weight, subcutaneous adipose tissue and circumferences were observed that were minimally associated with neonatal body composition, suggesting a stronger influence of prepregnancy BMI.
Study context
- Population
- Singleton pregnancies enrolled in US perinatal centres, 2009–2013 (NICHD Foetal Growth Studies)
- Participants
- 2,182 singleton pregnancies
- Exposure
- Prenatal weight and regional body composition trajectory classes, overall and by prepregnancy body mass index (BMI) group
- Outcome
- Neonatal body composition by trajectory class of prenatal weight, MUAC, triceps and subscapular skinfolds
Methodological detailsjoint latent trajectory models, weighted least squares
- Joint latent trajectory models
- Weighted least squares
Main finding
As reported in the abstract
- Trajectory patterns of co-occurring changes in weight, mid-upper arm circumference (MUAC), SSF and TSF identified overall and by BMI group
- 6
Observational data: associations, not effects.
Further findings
Neonatal adiposity by prepregnancy BMI
- Neonatal adiposity measures higher among infants of individuals with prepregnancy overweight/obesity
Original publication
Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies. Pediatr Obes. Published 5 January 2023. doi:10.
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