Effect of a Plant-Based vs Omnivorous Soul Food Diet on Weight and Lipid Levels Among African American Adults: A Randomized Clinical Trial
Authors' conclusion
In this randomized clinical trial examining weight loss and CVD risk factor reduction among African American adults, there were no differences between the groups, and the magnitude of changes overall was small.
Study context
- Population
- African American adults aged 18–65 years with overweight or obesity (BMI 25.0–49.9), without T2D, uncontrolled thyroid disease, recent weight loss or pregnancy; Columbia, South Carolina; mean age 48.4 years, 79% femaleweight obtained for 121
- Participants
- 159 adults
- Comparison
- Plant-based vs low-fat omnivorous soul food diet
- Vegann = 77
- Omnin = 82reference
- Primary endpoint
- Change in body weight and lipid measures
- Follow-up
- 12 months
Methodological details2 cohorts, assessor- and statistician-blinded, Classes weekly for 6 months, biweekly for 6 months, monthly for 12 months; online videoconference after March 2020
- 2 cohorts
- Assessor- and statistician-blinded
- Classes weekly for 6 months, biweekly for 6 months, monthly for 12 months; online videoconference after March 2020
Primary result
As reported in the abstract
Change in weight
Vegan
−2.39
mean · 95% CI −3.48–-1.30 · kg
Omni
−2.03
95% CI −3.07–-1.00 · kg
P = 0.64
Further findings
| Outcome | Vegan | Omnimg/dL | P value |
|---|---|---|---|
| Change in total cholesterol (primary lipid measure) · 12 monthsNo difference between groups | −1.05 (95% CI −9.60–7.50) mg/dL | 1.66 (95% CI −7.20–10.50) | P = 0.67 |
| Change in LDL-C (primary lipid measure) · 12 monthsNo difference between groups | mean −2.56 (95% CI −9.52–4.40) mg/dL | −0.79 (95% CI −7.98–6.40) | P = 0.73 |
| Weight change by cohort (cohort 1 pre-COVID-19 vs cohort 2 during COVID-19) · 12 monthsWeight loss significantly greater in cohort 1 | P = 0.01 |
- Weight change by cohort (cohort 1 pre-COVID-19 vs cohort 2 during COVID-19): Cohort 1 −3.45 (95% CI −4.67–-2.22) kg
- Weight change by cohort (cohort 1 pre-COVID-19 vs cohort 2 during COVID-19): Cohort 2 −1.24 (95% CI −2.24–-0.25) kg
Original publication
Effect of a Plant-Based vs Omnivorous Soul Food Diet on Weight and Lipid Levels Among African American Adults: A Randomized Clinical Trial. JAMA Netw Open. Published 3 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →