Premature cardiovascular disease mortality with overweight and obesity as a risk factor: estimating excess mortality in the United States during the COVID-19 pandemic
Authors' conclusion
Excess premature cardiovascular disease mortality in the USA for which overweight and obesity was a risk factor was considerably higher than for all causes, exacerbating adverse pre-pandemic trends. The contribution of COVID-19 to excess mortality appears significantly under-reported for home deaths.
Study context
- Population
- Premature (35–74 years) deaths in the USA, 2020
- Exposure
- Actual vs expected age-standardised death rates, March-December 2020
- Outcome
- Excess premature CVD mortality with diabetes, CKD, obesity, lipidemias or hypertensive heart disease on the death certificate (DKOLH-CVD)
- Follow-up
- March-December 2020
Methodological detailsmultiple cause of death data, negative binomial regression of monthly deaths 2010-19
- Multiple cause of death data
- Negative binomial regression of monthly deaths 2010-19
Main finding
As reported in the abstract
Excess DKOLH-CVD mortality
Observational data: associations, not effects.
Further findings
| Outcome | Males | Females |
|---|---|---|
| Excess all-cause mortality · March-December 2020 | 19% (UI 18–21%) | 16% (UI 14–17%) |
| Excess mortality with ≥2 DKOLH conditions reported | 40% (UI 37–43%) | 41% (UI 37–44%) |
| Excess mortality with obesity reported | 42% (UI 38–45%) | 47% (UI 43–51%) |
Share of excess mortality reported as due to COVID-19
- Excess DKOLH-CVD mortality reported as due to COVID-19
- One-half
- Excess all-cause deaths reported as due to COVID-19
- four-fifths
- Home deaths: excess mortality reported as due to COVID-19, each cause classification
- just over 10%
Original publication
Premature cardiovascular disease mortality with overweight and obesity as a risk factor: estimating excess mortality in the United States during the COVID-19 pandemic. Int J Obes (Lond). Published 2 February 2023. doi:10. 1038/ s41366-023-01263-y
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