Obesity

Premature cardiovascular disease mortality with overweight and obesity as a risk factor: estimating excess mortality in the United States during the COVID-19 pandemic

Int J Obes (Lond)Published Population-based mortality study

Authors' conclusion

Excess premature cardiovascular disease mortality in the USA for which overweight and obesity was a risk factor was considerably higher than for all causes, exacerbating adverse pre-pandemic trends. The contribution of COVID-19 to excess mortality appears significantly under-reported for home deaths.

Study context

Population
Premature (35–74 years) deaths in the USA, 2020
Exposure
Actual vs expected age-standardised death rates, March-December 2020
Outcome
Excess premature CVD mortality with diabetes, CKD, obesity, lipidemias or hypertensive heart disease on the death certificate (DKOLH-CVD)
Follow-up
March-December 2020
Methodological detailsmultiple cause of death data, negative binomial regression of monthly deaths 2010-19
  • Multiple cause of death data
  • Negative binomial regression of monthly deaths 2010-19

Main finding

As reported in the abstract

Excess DKOLH-CVD mortality

Observational data: associations, not effects.

Further findings

OutcomeMalesFemales
Excess all-cause mortality · March-December 202019% (UI 18–21%)16% (UI 14–17%)
Excess mortality with ≥2 DKOLH conditions reported40% (UI 37–43%)41% (UI 37–44%)
Excess mortality with obesity reported42% (UI 38–45%)47% (UI 43–51%)

Share of excess mortality reported as due to COVID-19

Excess DKOLH-CVD mortality reported as due to COVID-19
One-half
Excess all-cause deaths reported as due to COVID-19
four-fifths
Home deaths: excess mortality reported as due to COVID-19, each cause classification
just over 10%

Original publication

Premature cardiovascular disease mortality with overweight and obesity as a risk factor: estimating excess mortality in the United States during the COVID-19 pandemic. Int J Obes (Lond). Published 2 February 2023. doi:10.1038/s41366-023-01263-y

Composed by AI from the published abstract and checked against it. How Briefs are made →

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