Gestational diabetes & diabetes in pregnancy
Pregnancy outcomes of women with untreated ‘mild’ gestational diabetes (gestational diabetes by the WHO 2013 but not by the WHO-1999 diagnostic criteria) – A population-based cohort study
Authors' conclusion
Pregnancy outcomes of 'mild' GDM were worse compared to normal glucose tolerant women however these differences were explained by the pre-pregnancy BMI difference between groups.
Study context
- Population
- Pregnant women with a 3-point 75 g OGTT in a universal screening program, Hungary, 2009–2013screened with OGTT
- Participants
- 4,333 women
- Exposure
- Untreated 'mild' GDM vs NGT
- 'Mild' GDMn = 336
- NGTn = 3,303reference
- Outcome
- Pregnancy outcomes, 'mild' GDM vs NGT
Methodological detailsuniversal screening program
- Universal screening program
Main finding
As reported in the abstract
- GDM newborns heavier (mean difference, g)
- 142 (SE 50)
- Macrosomia (>4000 g), more frequent in GDM newborns: OR
- 1.85 (95% CI 1.35-2.54)
- Hypertension during pregnancy, more prevalent in GDM: OR
- 1.55 (95% CI 1.05-2.28)
- Induced delivery, more prevalent in GDM: OR
- 1.38 (95% CI 1.10-1.74)
- Instrumental delivery, more prevalent in GDM: OR
- 1.34 (95% CI 1.07-1.68)
- Acute caesarean section, more prevalent in GDM: OR
- 1.32 (95% CI 1.04-1.64)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate |
|---|---|
| Maternal characteristics'Mild' GDM vs NGT · age; older with 'Mild' GDM; SE 0.3 | mean difference 1.4 yrs |
| Maternal characteristics'Mild' GDM vs NGT · fasting blood glucose; higher with 'Mild' GDM; SE 0.02 | mean difference 1.0 mmol/l |
| Maternal characteristics'Mild' GDM vs NGT · 60-minute blood glucose; higher with 'Mild' GDM; SE 0.09 | mean difference 1.0 mmol/l |
| Maternal characteristics'Mild' GDM vs NGT · 120-minute blood glucose; higher with 'Mild' GDM; SE 0.06 | mean difference 0.4 mmol/l |
| Maternal characteristics'Mild' GDM vs NGT · blood pressure (first value); higher with 'Mild' GDM; SE 0.5 | mean difference 2.6 mmHg |
| Maternal characteristics'Mild' GDM vs NGT | mean difference 2.0 mmHg |
| Maternal characteristicsBetween 'Mild' GDM and NGT · weight gain; similar in both groups; SE 0.3 | mean difference −0.3 kg |
- Maternal characteristics: blood pressure (second value); higher with 'Mild' GDM; SE 0.5
Original publication
Pregnancy outcomes of women with untreated ‘mild’ gestational diabetes (gestational diabetes by the WHO 2013 but not by the WHO-1999 diagnostic criteria) – A population-based cohort study. Diabetes Res Clin Pract. Published 12 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →