Predictors of Exercise Performance in Type 1 Diabetes: The Role of Hypoglycaemia Fear, Glycaemic Control, and Vascular Health: A Retrospective Cross‐Sectional Study
Authors' conclusion
Fear of hypoglycaemia, HbA1c and microvascular complications are key determinants of reduced cardiopulmonary exercise performance in type 1 diabetes, highlighting the need for integrated physiological and psychological interventions.
Study context
- Population
- Adults with T1D in a multidisciplinary rehabilitation program at the University Medical Centre Groningen; median age 33 years, 76 females; median HbA1c 75 mmol/mol (IQR 63–93)
- Participants
- 122 adults
- Outcome
- Oxygen uptake, power output and heart rate at ventilatory thresholds and peak exercise
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Predictors of exercise performance (stepwise linear regression)
Higher HbA1c and VO2 at second ventilatory threshold, β
−0.085
Higher HbA1c and peak VO2, β
−0.089
Greater fear of hypoglycaemia and power output at second threshold, β
−21.95
Greater fear of hypoglycaemia and power output at peak exercise, β
−28.97
Observational data: associations, not effects.
Further findings
Hypoglycaemia fear survey (106 participants with data)
- Median Worry score
- 23.5
- Median Behaviour score
- 20.0
Original publication
Predictors of Exercise Performance in Type 1 Diabetes: The Role of Hypoglycaemia Fear, Glycaemic Control, and Vascular Health: A Retrospective Cross‐Sectional Study. Diabetes Obes Metab. Published 7 April 2026. doi:10. 1111/ dom. 70729
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