Type 1 diabetes

Predictors of Exercise Performance in Type 1 Diabetes: The Role of Hypoglycaemia Fear, Glycaemic Control, and Vascular Health: A Retrospective Cross‐Sectional Study

Diabetes Obes MetabPublished Retrospective cross-sectional study

Authors' conclusion

Fear of hypoglycaemia, HbA1c and microvascular complications are key determinants of reduced cardiopulmonary exercise performance in type 1 diabetes, highlighting the need for integrated physiological and psychological interventions.

Study context

Population
Adults with T1D in a multidisciplinary rehabilitation program at the University Medical Centre Groningen; median age 33 years, 76 females; median HbA1c 75 mmol/mol (IQR 63–93)
Participants
122 adults
Outcome
Oxygen uptake, power output and heart rate at ventilatory thresholds and peak exercise
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Predictors of exercise performance (stepwise linear regression)

Higher HbA1c and VO2 at second ventilatory threshold, β

−0.085

Higher HbA1c and peak VO2, β

−0.089

Greater fear of hypoglycaemia and power output at second threshold, β

−21.95

Greater fear of hypoglycaemia and power output at peak exercise, β

−28.97

Observational data: associations, not effects.

Further findings

Hypoglycaemia fear survey (106 participants with data)

Median Worry score
23.5
Median Behaviour score
20.0

Original publication

Predictors of Exercise Performance in Type 1 Diabetes: The Role of Hypoglycaemia Fear, Glycaemic Control, and Vascular Health: A Retrospective Cross‐Sectional Study. Diabetes Obes Metab. Published 7 April 2026. doi:10.1111/dom.70729

Composed by AI from the published abstract and checked against it. How Briefs are made →

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