Predictive Risk Score for Postparathyroidectomy Hungry Bone Syndrome in Patients With Secondary Hyperparathyroidism
Authors' conclusion
We developed a weighted risk score that effectively stratifies patients by risk for developing HBS after parathyroidectomy. This tool can be used to counsel patients and to identify patients who may not require postoperative hospitalization.
Study context
- Population
- Patients who underwent parathyroidectomy for secondary hyperparathyroidism, US Renal Data System (2010–2021)
- Participants
- 17,074 patients
- Exposure
- Hungry bone syndrome (HBS) vs No HBS
- Outcome
- Development of HBS; risk score to stratify patients by HBS risk
Methodological detailsrisk score development, multivariable logistic regression
- Risk score development
- Multivariable logistic regression
Main finding
As reported in the abstract
- Developed HBS
- 19.4%
- Risk score total possible points
- 6
- HBS rate with 0 points
- 8%
- HBS rate with 6 points
- 44%
- Risk score PPV (poor)
- 20.3%
- Risk score NPV (excellent)
- 89.3%
Observational data: associations, not effects.
Further findings
ICU admission · more common with HBS
P < 0.001
Original publication
Predictive Risk Score for Postparathyroidectomy Hungry Bone Syndrome in Patients With Secondary Hyperparathyroidism. J Clin Endocrinol Metab. Published 28 October 2023. doi:10.
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