Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China
An erratum to this article was published (Cardiovasc Diabetol, 29 Jun 2023 ↗)
Authors' conclusion
Prediabetes accounts for more than one-third of the young adults undergoing CAG and was associated with an increased risk of all-cause mortality, active prevention strategy should be considered for these patients.
Study context
- Population
- Young patients (men aged < 45 years, women aged < 55 years) undergoing coronary angiography (CAG), China
- Participants
- 8,868 patients
- Exposure
- Prediabetes and diabetes vs normoglycemia
- Prediabetesn = 3,240
- Diabetesn = 2,218
- Outcome
- All-cause mortality
- Follow-up
- Median 4.92 years
Methodological detailsmulticenter
- Multicenter
Main finding
As reported in the abstract
Each group vs normoglycemicAdjusted hazard ratio (95% CI)P value
Prediabetes
1.24(1.04–1.49)
P = 0.019Diabetes
1.46(1.2–1.79)
P < 0.001- Deaths during follow-up
- 728
Observational data: associations, not effects.
Further findings
| Outcome | Prediabetes | Diabetes |
|---|---|---|
| Prevalence of prediabetes and diabetes | 36.5% | 25.0% |
All-cause mortality by comorbidity subgroup
- Diabetes and prediabetes increased the risk of death mainly in patients without comorbidities
Original publication
Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China. Cardiovasc Diabetol. Published 1 March 2023. doi:10. 1186/ s12933-023-01776-w
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