Pre‐polycystic ovary syndrome and polymenorrhoea as new facets of polycystic ovary syndrome (PCOS): Evidences from a single centre data set
Authors' conclusion
The metabolic disturbances observed in Pre-PCOS women highlight the need to reassess diagnostic criteria. Including the polymenorrhoea subcategory in PCOS criteria is recommended due to similar metabolic dysfunctions as the oligomenorrhoea group.
Study context
- Population
- Women with PCOS-like characteristics and age-matched healthy women, single centre6,463 with PCOS-like features
- Participants
- 5,174 / 538 / 121 / 78 / 3,142
- Exposure
- PCOS vs partial PCOS phenotypes vs healthy controls
- PCOSn = 5,174
- Hyperandrogenism (HA)n = 538
- Oligo-amenorrhoea (OA)n = 121
- Polycystic ovarian morphology (PCOM)n = 78
- Healthy controlsn = 3,142reference
- Outcome
- Clinical, hormonal and metabolic characteristics
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Pre-PCOS
737
Observational data: associations, not effects.
Further findings
Common clinical features
- Oligomenorrhoea
- 75.5%
- Hirsutism
- 82.9%
- Obesity
- 27.2%
- Hypertension
- 1.6%
- Metabolic syndrome
- 19.6%
- DM
- 5.6%
Polymenorrhoea subgroup vs oligomenorrhoea subgroup
- Polymenorrhoea subgroup
- 5.9%
- Lower BMI and serum testosterone, but similar mFG score, plasma glucose, insulin and lipid levels vs oligomenorrhoea
Original publication
Pre‐polycystic ovary syndrome and polymenorrhoea as new facets of polycystic ovary syndrome (PCOS): Evidences from a single centre data set. Clin Endocrinol (Oxf). Published 1 September 2023. doi:10.
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