Pre-hospital glycemia as a biomarker for in-hospital all-cause mortality in diabetic patients - a pilot study
Authors' conclusion
Despite the pilot nature and modest sample size, this study marks the beginning of exploration into personalized glycemic control for hospitalized patients with T2DM. Pre-hospital blood glucose levels and related variables derived from it can serve as biomarkers for all-cause mortality during hospitalization.
Study context
- Population
- Hospitalized patients with T2D
- Participants
- 120 patients
- Outcome
- 30-day mortality risk (in-hospital all-cause mortality)
- Follow-up
- 30 days
Methodological detailsprognostic modelling, machine learning and classical statistical analysis, machine learning (AdaBoost-FAS)
- Prognostic modelling, machine learning and classical statistical analysis
- Machine learning (AdaBoost-FAS)
Performance
As reported in the abstract
Discrimination of mortality
- Novel index (ratio of intra-hospital glycemic variability to pre-hospitalization glycemic mean), together with in-hospital glycemic variability, discriminated between patients with higher and lower mortality rates
Original publication
Pre-hospital glycemia as a biomarker for in-hospital all-cause mortality in diabetic patients - a pilot study. Cardiovasc Diabetol. Published 3 May 2024. doi:10.
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