Postprandial Glycemic Control With Automated Insulin Delivery With Control‐ IQ Technology: The Impact of Meal Composition
Authors' conclusion
Despite a substantial autonomous increase in insulin delivery, AID systems using Control-IQ technology and a standard CHC-based pre-meal bolus have not achieved adequate postprandial glycemic control after HF and HP meals.
Study context
- Population
- Adolescents with T1D using AID (Tandem Tslim X2 with Control-IQ); Carbohydrate counting (CHC)-based bolus 15 min before each meal
- Participants
- 25 adolescents
- Exposure
- High-fat (HF) and high-protein (HP) meals vs standard meal with AID and CHC-based premeal bolus
- Outcome
- Time in range (TIR) (70-180 mg/dL)
- Follow-up
- 6 h
Main finding
As reported in the abstract
HF vs Standard meal: P < 0.01 · HP vs Standard meal: P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | HF | HP | P value |
|---|---|---|---|
| AID insulin delivery above pre-programmed basal · 6 hHF vs Standard meal · vs pre-programmed basal | +26% | +55% | P < 0.05 |
| AID insulin delivery above pre-programmed basal · 6 hHP vs Standard meal · vs pre-programmed basal | P < 0.001 |
Postprandial glucose exposure (AUC above 140 and 180 mg/dL) · 3 and 6 h
- Significantly higher after HF and HP meals vs standard meal at both 3 and 6 h
Safety
- More insulin delivered without increasing hypoglycemia
Original publication
Postprandial Glycemic Control With Automated Insulin Delivery With Control‐ IQ Technology: The Impact of Meal Composition. Diabetes Obes Metab. Published 20 July 2026. doi:10.
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