Post-OGTT hypoglycaemia in newly diagnosed type 2 diabetes: frequency, characteristics and cluster assignment
Authors' conclusion
Post-OGTT hypoglycaemia is present in a subset of individuals newly diagnosed with type 2 diabetes and is associated with higher insulin sensitivity.
Study context
- Population
- Individuals newly diagnosed with T2D undergoing extended 75 g OGTT97 OGTTs analysed
- Participants
- 97 individuals
- Exposure
- Post-OGTT hypoglycaemia vs no hypoglycaemia
- Outcome
- Frequency of post-OGTT hypoglycaemia (glucose ≤3.9 mmol/l at 180 min)
- Follow-up
- 180 min
Methodological detailsextended (180 min) 75 g OGTT
- Extended (180 min) 75 g OGTT
Main finding
As reported in the abstract
Post-OGTT hypoglycaemia (glucose ≤3.9 mmol/l at 180 min)
Frequency of post-OGTT hypoglycaemia among OGTTs analysed
8.2%
Observational data: associations, not effects.
Further findings
Metabolic characteristics: hypoglycaemia vs no hypoglycaemia
- Significantly lower BMI and higher insulin sensitivity with post-OGTT hypoglycaemia
- No differences in beta cell function
Ahlqvist cluster assignment
- All individuals with hypoglycaemia assigned to mild obesity- or age-related diabetes clusters
Original publication
Post-OGTT hypoglycaemia in newly diagnosed type 2 diabetes: frequency, characteristics and cluster assignment. Diabetologia. Published 27 March 2026. doi:10.
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