Physical performance and sarcopenia assessment in patients with a recent fracture visiting the Fracture Liaison Service
Authors' conclusion
Physical performance is significantly lower in FLS patients compared to healthy peers, especially in patients with hip, major or prevalent VF.
Study context
- Population
- Patients with a recent clinical fracture attending the Fracture Liaison Service (median age 66; 70.7% females; 3.9 months after fracture)
- Participants
- 1,789 consecutive Fracture Liaison Service (FLS) patients
- Exposure
- FLS patients with a recent fracture vs population reference data
- Outcome
- Proportion with impaired/poor physical performance (CST, HGS, TUG, 6MWT; Z-score < −1 vs reference data) and prevalence of sarcopenia (EWGSOP2)
Methodological detailsconsecutive patients, comparison with reference data (Z-scores), linear regression
- Consecutive patients
- Comparison with reference data (Z-scores)
- Linear regression
Main finding
As reported in the abstract
- Impaired/poor performance, chair stand test (CST)
- 39.2%
- Impaired/poor performance, handgrip strength (HGS)
- 30.4%
- Impaired/poor performance, timed-up-and-go (TUG)
- 21.9%
- Impaired/poor performance, 6MWT
- 71.5%
- Sarcopenia
- 2.8%
Observational data: associations, not effects.
Further findings
CST Z-score by fracture type (linear regression)
- Major fracture, regression coefficient (B) (95%CI)
- B = - 0.25 [- 0.34, - 0.16]
- Hip fracture, B (95%CI)
- B = - 0.32 [- 0.47, - 0.17]
- ≥ 1 prevalent vertebral fracture (VF), B (95%CI)
- B = - 0.22 [- 0.34, - 0.11]
- Lower Z-scores (P < 0.001)
TUG Z-score by fracture type (linear regression)
- Major fracture, B (95%CI)
- B = - 0.54 [- 0.75, - 0.33]
- Hip fracture, B (95%CI)
- B = - 1.72 [- 2.08, −1.35]
- ≥ 1 prevalent VF, B (95%CI)
- B = - 0.61 [- 0.88, - 0.57]
- Lower Z-scores (P < 0.001)
6MWT Z-score by fracture type (linear regression)
- Major fracture, B (95%CI)
- B = - 0.34 [- 0.47, - 0.21]
- ≥ 1 prevalent VF, B (95%CI)
- B = - 0.36 [- 0.53, - 0.19]
- Lower Z-scores (P < 0.001)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Physical performance and sarcopenia assessment in patients with a recent fracture visiting the Fracture Liaison Service. Osteoporos Int. Published 13 February 2024. doi:10.
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