Physical activity and sedentary behaviour in relation to body composition, estimated insulin sensitivity and arterial stiffness in adults with type 1 diabetes
Authors' conclusion
Higher levels of PA, lower sedentary behaviour and greater exercise capacity are favourably associated with long-term glycaemic control, body composition, insulin dosage, estimated insulin sensitivity and arterial stiffness in adults with T1D. Therefore, regular PA and limiting sedentary time should be encouraged to improve metabolic and cardiovascular health in this population. Future longitudinal studies should explore mutual interactions and synergistic effects of PA on these outcomes.
Study context
- Population
- Adults with T1D
- Participants
- 54 adults
- Outcome
- Association of daily PA levels and sedentary behaviour with body composition, estimated insulin sensitivity and arterial stiffness
Methodological detailsPA and sedentary behaviour measured by accelerometry for 7 days; VO2max by cardiopulmonary exercise test; body composition by DXA; arterial stiffness by cf-PWV
- PA and sedentary behaviour measured by accelerometry for 7 days; VO2max by cardiopulmonary exercise test; body composition by DXA; arterial stiffness by cf-PWV
Main finding
As reported in the abstract
- Lower 10-year HbA1c associated moderately with all PA measures
- Favourable moderate associations between PA measures and BMI, waist, visceral adipose tissue (VAT) but not FM and LM
- PA measures favourably associated with lower total daily insulin dose and higher estimated glucose disposal rate (eGDR)
- All PA parameters associated moderately with cf-PWV, but not independent of traditional risk factors
- VO2max inversely associated with cf-PWV independent of age, T1D duration and 24-hour mean blood pressure
Observational data: associations, not effects.
Original publication
Physical activity and sedentary behaviour in relation to body composition, estimated insulin sensitivity and arterial stiffness in adults with type 1 diabetes. Diabetes Res Clin Pract. Published 16 September 2024. doi:10.
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