Physical activity in relation to metabolic health and obesity: The Feel4Diabetes study
Authors' conclusion
A universally accepted definition for MHO is needed. Being physically active can contribute to a metabolically healthy profile even in the presence of obesity; still, MHO is a transient condition and physical activity alone may not be an adequate factor for its maintenance.
Study context
- Population
- Men and women from families at risk of developing diabetes (Feel4Diabetes); classified as obese or non-obese, metabolic health by five existing definitions; physical activity by International Physical Activity Questionnaire and pedometers
- Participants
- 2,848 men
- Exposure
- Metabolically healthy obese (MHO) vs metabolically unhealthy obese (MUO); physical activity as predictor of metabolic health
- Outcome
- Physical activity levels in association with metabolic health; stability of MHO phenotypes
- Follow-up
- 2 years
Methodological details2-year follow-up
- 2-year follow-up
Main finding
As reported in the abstract
Predictors of metabolic health in individuals with obesity
Prevalence of MHO phenotype across definitions
0% to 20.2%
Daily sitting hours, OR
1.055
95% CI 1.009–1.104
Daily steps (per 500), OR
0.934
95% CI 0.896–0.973
Observational data: associations, not effects.
Further findings
Phenotype transition · 2 years
- Baseline MHO transitioned to MUO
- 44.1%
- Baseline MUO remained MUO
- 84.0%
- Physical activity not a major determinant of transitioning; daily steps associated with maintenance of metabolic health in non-obese
Original publication
Physical activity in relation to metabolic health and obesity: The Feel4Diabetes study. Diabetes Obes Metab. Published 19 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →