Reproductive endocrinology

Phenotype Prevalence and Health-Related Quality of Life of Lebanese Women With Polycystic Ovary Syndrome

Endocr PractPublished Cross-sectional study

Authors' conclusion

Most Lebanese women with PCOS present phenotype A and have a serious impairment in their health-related quality of life, particularly in the menstrual and emotional domains. This highlights the need for community and individual support.

Study context

Population
Lebanese women with polycystic ovary syndrome (PCOS)
Participants
322 women
Outcome
Phenotype prevalence and health-related quality of life (PCOSQ)

Main finding

As reported in the abstract

Phenotype A (most common phenotype)
67%
Mean total score of all PCOS questionnaire (PCOSQ) domains
3.61 ± 1.60
Menstrual problems domain mean score (greatest concern)
3.31 ± 1.26
Emotion domain mean score
3.33 ± 1.22
Weight domain mean score
3.41 ± 2.12
Body hair domain mean score
3.86 ± 1.79
Infertility domain mean score (least concern)
4.15 ± 1.61

Observational data: associations, not effects.

Further findings

Waist circumference and Body Mass Index (BMI) by phenotype

High waist circumference and higher BMI reported mostly in classic vs nonclassic phenotypes
P < 0.05

Age and PCOSQ domain scores

Age negatively correlated only to weight domain score
r = −0.17, P = .002

BMI and PCOSQ domain scores

BMI associated with emotion domain score
P = 0.017
BMI associated with weight domain score
P < 0.001
  • BMI associated only with emotion and weight domains

PCOSQ impairment by comorbidity

Bigger impairment in nearly all PCOSQ subscales with abdominal obesity, glucose intolerance and increased blood pressure
P < 0.05

Original publication

Phenotype Prevalence and Health-Related Quality of Life of Lebanese Women With Polycystic Ovary Syndrome. Endocr Pract. Published 6 December 2022. doi:10.1016/j.eprac.2022.12.001

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