Diabetes technology

Performance of the Dexcom G6 Continuous Glucose Monitoring System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation

Diabetes CarePublished Diagnostic accuracy study

Authors' conclusion

Cardiac surgery using hypothermic ECC challenges the accuracy of the Dexcom G6 CGM although recovery appears to occur thereafter.

Study context

Population
Subjects undergoing cardiac surgery with hypothermic extracorporeal circulation (ECC); 11 received deep hypothermic circulatory arrest (DHCA)11 with DHCA
Participants
16 subjects
Comparison
Dexcom G6 continuous glucose monitoring (CGM) vs arterial blood glucose as reference
  • Dexcom G6n = 16
Outcome
Intrasurgery accuracy of Dexcom G6 vs reference
Follow-up
During surgery

Performance

As reported in the abstract

Test or modelMean absolute relative difference (MARD) (256 pairs)Signed relative differencePairs in Clarke error grid zones A or BReadings fulfilling ISO 15197:2013
Dexcom G623.8%−13.7%86.3%41.0%

Dexcom G6

Mean absolute relative difference (MARD) (256 pairs)23.8%
Signed relative difference−13.7%
Pairs in Clarke error grid zones A or B86.3%
Readings fulfilling ISO 15197:201341.0%

Further findings

OutcomeDexcom G6
Accuracy during ECC
MARD (154 pairs)29.1%
Signed relative difference−26.6%
Accuracy immediately after DHCA
MARD (10 pairs)41.6%
Signed relative difference−41.6%
Accuracy postsurgery
MARD15.0%

Original publication

Performance of the Dexcom G6 Continuous Glucose Monitoring System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation. Diabetes Care. Published 21 February 2023. doi:10.2337/dc22-2260

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