Performance of the Dexcom G6 Continuous Glucose Monitoring System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation
Authors' conclusion
Cardiac surgery using hypothermic ECC challenges the accuracy of the Dexcom G6 CGM although recovery appears to occur thereafter.
Study context
- Population
- Subjects undergoing cardiac surgery with hypothermic extracorporeal circulation (ECC); 11 received deep hypothermic circulatory arrest (DHCA)11 with DHCA
- Participants
- 16 subjects
- Comparison
- Dexcom G6 continuous glucose monitoring (CGM) vs arterial blood glucose as reference
- Dexcom G6n = 16
- Outcome
- Intrasurgery accuracy of Dexcom G6 vs reference
- Follow-up
- During surgery
Performance
As reported in the abstract
| Test or model | Mean absolute relative difference (MARD) (256 pairs) | Signed relative difference | Pairs in Clarke error grid zones A or B | Readings fulfilling ISO 15197:2013 |
|---|---|---|---|---|
| Dexcom G6 | 23.8% | −13.7% | 86.3% | 41.0% |
Dexcom G6
Mean absolute relative difference (MARD) (256 pairs)23.8%
Signed relative difference−13.7%
Pairs in Clarke error grid zones A or B86.3%
Readings fulfilling ISO 15197:201341.0%
Further findings
| Outcome | Dexcom G6 |
|---|---|
| Accuracy during ECC | |
| MARD (154 pairs) | 29.1% |
| Signed relative difference | −26.6% |
| Accuracy immediately after DHCA | |
| MARD (10 pairs) | 41.6% |
| Signed relative difference | −41.6% |
| Accuracy postsurgery | |
| MARD | 15.0% |
Original publication
Performance of the Dexcom G6 Continuous Glucose Monitoring System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation. Diabetes Care. Published 21 February 2023. doi:10. 2337/ dc22-2260
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