Obesity

Perceptions of GLP-1 RA Use for Children With Obesity Among Caregivers With Food Insecurity: A Qualitative Study

JAMA Netw OpenPublished Qualitative study

Authors' conclusion

In this qualitative study, children's caregivers experiencing food insecurity expressed interest in both lifestyle-only and medication-inclusive approaches, with decisions shaped by lived experience, perceptions of safety, and values. Shared decision-making conversations in clinical settings that acknowledge these influences-and address barriers to both treatment options-could foster more family-centered, equitable, and effective pediatric obesity care.

Study context

Population
Caregivers (aged ≥18 years) of children (aged <18 years) with obesity and MASLD who screened positive for moderate-severe food insecurity; pediatric gastroenterology clinics of a regional academic health care system20 analysed
Participants
37 participants
Outcome
Factors influencing caregiver decisions regarding medication use for their child's metabolic disease
Methodological detailssemistructured interviews, inductive thematic analysis, 21 of 37 eligible caregivers completed interviews, Interviews via telephone or video in participants' preferred language, December 1, 2023 to April 30, 2024
  • Semistructured interviews
  • Inductive thematic analysis
  • 21 of 37 eligible caregivers completed interviews
  • Interviews via telephone or video in participants' preferred language, December 1, 2023 to April 30, 2024

Main finding

As reported in the abstract

Factors influencing caregiver decision-making about GLP-1 RA use

Desired adjunct pharmacotherapy for their child

12

60%

Further findings

Prior lifestyle care

Met with a dietitian
10 (50%)
All caregivers received lifestyle-related recommendations and dietetics referral

Original publication

Perceptions of GLP-1 RA Use for Children With Obesity Among Caregivers With Food Insecurity: A Qualitative Study. JAMA Netw Open. Published 2 January 2026. doi:10.1001/jamanetworkopen.2025.52825

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