Perceptions of GLP-1 RA Use for Children With Obesity Among Caregivers With Food Insecurity: A Qualitative Study
Authors' conclusion
In this qualitative study, children's caregivers experiencing food insecurity expressed interest in both lifestyle-only and medication-inclusive approaches, with decisions shaped by lived experience, perceptions of safety, and values. Shared decision-making conversations in clinical settings that acknowledge these influences-and address barriers to both treatment options-could foster more family-centered, equitable, and effective pediatric obesity care.
Study context
- Population
- Caregivers (aged ≥18 years) of children (aged <18 years) with obesity and MASLD who screened positive for moderate-severe food insecurity; pediatric gastroenterology clinics of a regional academic health care system20 analysed
- Participants
- 37 participants
- Outcome
- Factors influencing caregiver decisions regarding medication use for their child's metabolic disease
Methodological detailssemistructured interviews, inductive thematic analysis, 21 of 37 eligible caregivers completed interviews, Interviews via telephone or video in participants' preferred language, December 1, 2023 to April 30, 2024
- Semistructured interviews
- Inductive thematic analysis
- 21 of 37 eligible caregivers completed interviews
- Interviews via telephone or video in participants' preferred language, December 1, 2023 to April 30, 2024
Main finding
As reported in the abstract
Factors influencing caregiver decision-making about GLP-1 RA use
Desired adjunct pharmacotherapy for their child
12
60%
Further findings
Prior lifestyle care
- Met with a dietitian
- 10 (50%)
- All caregivers received lifestyle-related recommendations and dietetics referral
Original publication
Perceptions of GLP-1 RA Use for Children With Obesity Among Caregivers With Food Insecurity: A Qualitative Study. JAMA Netw Open. Published 2 January 2026. doi:10. 1001/ jamanetworkopen. 2025. 52825
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