Paediatric new onset type 1 diabetes and diabetic ketoacidosis during the COVID-19 pandemic in Malaysia
Authors' conclusion
New onset T1DM increased during the pandemic, with a greater proportion having severe DKA. Further studies are required to evaluate the mechanism leading to this rise to guide intervention measures.
Study context
- Population
- Paediatric patients with new onset T1D in Klang Valley, Malaysia5-year study period
- Participants
- 180 patients
- Exposure
- Pandemic vs pre-pandemic period
- Pandemicn = 109
- Pre-pandemicn = 71reference
- Outcome
- Frequency, demographics and clinical characteristics of new onset T1D
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Frequency of new onset T1D
Increase in frequency of T1D during the pandemic; cases in 2021
52
Cases in 2020
38
Cases in 2019
27
Cases in 2018
30
Observational data: associations, not effects.
Further findings
Presentation with DKA
Severe DKA
Presentation with diabetic ketoacidosis (DKA)
- Significantly greater proportion during the pandemic
Severe DKA
- Greater proportion during the pandemic
Serum glucose
- Significantly higher during the pandemic (28.2 mmol vs 25.9 mmol/L)
Venous pH
- Lower during the pandemic (7.10 vs 7.16)
HbA1c
- HbA1c was unchanged
Original publication
Paediatric new onset type 1 diabetes and diabetic ketoacidosis during the COVID-19 pandemic in Malaysia. Diabetes Res Clin Pract. Published 25 October 2023. doi:10.
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